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March 22 2018

Antioxidants and amino acids could play role in the treatment of psychosis

A scientific paper has revealed that some nutrients found in food may help reduce the symptoms of psychotic illness, when used in the early stages of treatment.

March 21 2018

Intense exercise before taking anti-psychotic meds may prevent weight gain, diseases

Researchers found evidence that a single bout of exhaustive exercise protects against acute olanzapine-induced hyperglycemia.

March 13 2018

Helpful B cells lend a hand to developing neurons

Neuron myelination is critical to early mental development, and defects in myelination have been linked to neurodevelopmental disorders. Researchers found that B immune cells reside in the brains of developing mice, and play a key role in the myelination of neurons by oligodendrocytes. The findings suggest a new avenue of exploration for understanding the origin of disorders such as autism and schizophrenia.

March 12 2018

Childhood trauma link offers treatment hope for people with schizophrenia

Researchers have shown that childhood sexual, physical and emotional abuse are associated with severe hallucinations in schizophrenia and other psychotic disorders.

February 27 2018

Genetics researchers close in on schizophrenia

Researchers have discovered 50 new gene regions that increase the risk of developing schizophrenia. They have also used state-of-the-art information about brain development to accurately pinpoint new genes and biological pathways implicated in this disorder.

February 22 2018

Looking for the origins of schizophrenia

Schizophrenia may be related to neurodevelopment changes, including brain's inability to create the appropriate vascular system, according to new study. The results broaden the understanding about the causes of this severe and disabling disorder, which affects about 1 percent of the world's population.

February 21 2018

Novel mechanism behind schizophrenia uncovered

Researchers have uncovered a novel mechanism in which a protein--neuregulin 3--controls how key neurotransmitters are released in the brain during schizophrenia. The protein is elevated in people with schizophrenia and other severe mental illnesses, but the study is the first to investigate how it causes such severe mental illness.

February 16 2018

Link between hallucinations and dopamine not such a mystery, finds study

Researchers have found that people with schizophrenia who experience auditory hallucinations tend to hear what they expect, an exaggerated version of a perceptual distortion that is common among other people without hallucinations. The researchers found that elevated dopamine could make some patients rely more on expectations, which could then result in hallucinations.

February 13 2018

Pimavanserin: Relief from psychosis in dementia, without devastating side-effects

New research has found that pimavanserin significantly improves psychosis symptoms in people with Alzheimer's disease, without the devastating side-effects of currently used antipsychotics. The research found an even greater benefit in those with the most severe psychotic symptoms.

February 08 2018

Autism, schizophrenia, bipolar disorder share molecular traits, study finds

Most medical conditions are largely defined by their physical symptoms. Psychiatric illnesses, however, are largely defined by a person's behavior. A new study challenges that distinction, identifying many shared -- and distinct -- patterns of gene expression in the brains of people with autism, schizophrenia and bipolar disorder. The data hint at potential targets that may one day lead to new treatment approaches.

February 01 2018

Zeroing in on dopamine

Scientists have identified the molecular machinery responsible for secretion of the neurotransmitter dopamine, opening the door for strategies to precision target dopamine release to treat disorders such as Parkinson's and addiction.

Food preservative enhances schizophrenia treatment

A randomized, double-blind, placebo-controlled trial shows that sodium benzoate improves symptoms in clozapine-resistant schizophrenia.

January 31 2018

Molecular secrets revealed: Antipsychotic docked in its receptor

Scientists have deciphered the molecular structure of a widely prescribed antipsychotic docked in its key receptor. They are hopeful that this discovery may hold secrets to designing better treatments for schizophrenia, bipolar disorder, and other mental illnesses.

January 24 2018

Breakthrough could lead to better antipsychotic drugs

Although antipsychotic drugs are among the most widely prescribed medications, individuals with schizophrenia, bipolar disorder and autism-spectrum disorders often experience severe side effects because the drugs interact with dozens of other brain receptors. Now, scientists have solved the first high-resolution crystal structure of the dopamine 2 receptor (DRD2) bound to the antipsychotic drug risperidone, yielding a long-awaited tool for drug developers, psychiatrists, and neuroscientists.

January 18 2018

Postmortem schizophrenia study identifies shifts in patterns of glutamate and GABA in visuospatial working memory network

Disruptions in certain regions of the visuospatial working memory network may lead to its impairment in schizophrenia, according to a new study.

January 03 2018

Rare forms of 'thunder' protein may be linked to schizophrenia

Researchers report they have identified rare genetic variations in a protein called Thorase, which is responsible for breaking down receptors at the connections between neurons in the brain.

December 13 2017

Treatable Condition Could Be Mistaken for Schizophrenia or Bipolar Disorder

Researchers believe that a significant number of people diagnosed with schizophrenia or bipolar disorder may actually have a treatable immune system condition. A new research study could have a significant impact on the millions diagnosed with schizophrenia or bipolar disorder, including many homeless.

December 12 2017

New therapy can help schizophrenia sufferers re-engage socially

A new therapy aimed at helping young people suffering from schizophrenia to reconnect and engage with the world around them has had promising results, according to a new study.

December 11 2017

Updated brain cell map connects various brain diseases to specific cell types

Researchers have developed new single-cell sequencing methods that could be used to map the cell origins of various brain disorders, including Alzheimer's, Parkinson's, schizophrenia and bipolar disorder. By analyzing individual nuclei of cells from adult human brains, researchers have identified 35 different subtypes of neurons and glial cells and discovered which of these subtypes are most susceptible to common risk factors for different brain diseases.

December 08 2017

How individuals with schizophrenia view their experiences and confidence in judgments may influence treatment targets

A schizophrenia patient's own perceptions of their experiences -- and confidence in their judgments -- may be factors that can help them overcome challenges to get the life they wish, suggests a new paper.
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