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August 13 2018

Switching anti-psychotic medications doesn't improve outcomes in first episode schizophrenia patient

Switching anti-psychotic medications does not improve clinical outcomes in patients with first-episode schizophrenia who haven't responded to treatment, researchers have shown for the first time.

August 09 2018

Targeting a brain mechanism could treat aggression

Neuroscientists have identified a brain mechanism that is linked to aggression and violent behavior, potentially forming the basis for treating aggression in several psychiatric disorders.

July 12 2018

Machine learning helps to predict the treatment outcomes of schizophrenia

Researchers have used artificial intelligence to help identify patients suffering from schizophrenia and to ascertain if they would respond to treatment.

Treatment prevents symptoms of schizophrenia in tests with rats

Researchers carried out studies in animal model that mimics condition in children and adolescents considered at risk for development of the disease in adulthood. Young and hypertense rats displaying cognitive and social impairments as well as hyperlocomotion have reached a healthy adulthood after being treated with daily doses of sodium nitroprusside doses for 30 days.

July 11 2018

Stress affects people with schizophrenia differently

Stressful situations affect the brain and body differently in people with schizophrenia compared to people without the mental illness or individuals at high risk for developing psychosis, a new study shows. The relationship between two chemicals released when people experienced stress -- one released in the brain and the other in saliva -- differs in people with schizophrenia. The discovery may provide clues into how to act early to prevent schizophrenia.

June 22 2018

People with schizophrenia account for more than one in 10 suicide cases

A new study shows that people with schizophrenia account for more than one in 10 cases of suicide in Ontario, and that young people are disproportionately affected. People with schizophrenia also had more contact with the health care system, pointing to an opportunity to intervene. The researchers emphasize the need for early suicide risk assessments to reduce risks.

June 19 2018

Genes associated with infantile forms of schizophrenia identified

Scientists have identified novel genes associated with a specific form of schizophrenia.

June 18 2018

Rare mutation of gene carried by Quebec family gives insight into how the brain is wired

The study of a Quebec family with an unusual gene provides novel insight into how our brain is built and, according to scientists, offers a better understanding of psychiatric disorders such as depression, addictions and schizophrenia.

June 08 2018

Scientists discover schizophrenia gene roles in brain development

A USC research team identified 150 proteins affecting cell activity and brain development that contribute to mental disorders, including schizophrenia, bipolar condition and depression.

May 30 2018

Promise of faster, more accessible schizophrenia diagnosis

A new study shows how the hand-held device RETeval may prove to be a more accessible way to diagnose schizophrenia, predict relapse and symptom severity, and assess treatment effectiveness.

May 29 2018

Scientists show how brain circuit generates anxiety

Neuroscientists have identified a neural circuit in the amygdala, the brain's seat of emotion processing, that gives rise to anxiety. Their insight has revealed the critical role of a molecule called dynorphin, which could serve as a target for treatment of anxiety-related disorders including post-traumatic stress disorder (PTSD).

May 28 2018

Genes, environment and schizophrenia: New study finds the placenta is the missing link

New research shines a spotlight on the placenta's critical role in the nature versus nurture debate and how it confers risk for schizophrenia and likely other neurodevelopmental disorders including ADHD, autism, and Tourette syndrome. This new scientific frontier, with far-reaching implications for maternal and child health, creates the possibility that scientists can more accurately predict who is at risk of mental illness, and develop strategies to prevent or lessen their occurrence by increasing the resiliency and health of the placenta.

May 21 2018

Cell types underlying schizophrenia identified

Scientists have identified the cell types underlying schizophrenia. The findings offer a roadmap for the development of new therapies to target the condition.

May 05 2018

Structural variation in key brain receptor enables it to cope with hostile condition

During a stroke or an epileptic seizure, neurons in affected parts of the brain fire at an abnormally rapid rate. One byproduct of this condition is that the pH of the brain drops markedly, rendering the local environment inhospitably acidic. Scientists have imaged a structural variant of the brain's MNDA receptor that can operate in this hostile environment.

May 03 2018

Even brief maternal deprivation early in life alters adult brain function and cognition: Rat study

When a baby is taken from its mother for even a brief period early in life, this traumatic event significantly alters the future, adult function of the brain, according to a new animal model study. These changes in the brain are similar to disturbances in brain structure and function that are found in people at risk for neuropsychiatric disorders, such as schizophrenia.

April 25 2018

Brain folding provides researchers with an accurate marker to predict psychosis

By using images of the brain to look at how the grey matter is folded on itself, researchers can predict which high-risk patients will develop psychosis with more than 80 per cent accuracy.

April 17 2018

Resilience counteracts effects of childhood abuse and neglect on health

Researchers have determined that psychological resilience has a positive effect on health outcomes for people living with schizophrenia. This is the first study to quantitatively assess the effects of both childhood trauma and psychological resilience on health and metabolic function in people living with schizophrenia.

April 05 2018

Attention deficit disorders could stem from impaired brain coordination

Researchers have discovered how two brain regions work together to maintain attention, and how discordance between the regions could lead to attention deficit disorders, including schizophrenia, bipolar disorder, and major depression.

April 04 2018

Prescribing antipsychotic medication for children with autism

A new study has suggested that children with intellectual difficulty or autism are more likely to be given antipsychotic medication from a younger age than those without intellectual disability and have higher rates of hospitalisation for depression and for injury and also are at risk of other medical side effects.

April 02 2018

Novel PET imaging agent could help guide therapy for brain diseases

Researchers have developed a new PET imaging agent that could help guide and assess treatments for people with various neurological diseases, including Alzheimer's, Parkinson's, and multiple sclerosis. The agent targets receptors in nerve cells in the brain that are involved in learning and memory.
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